Oil on canvas.
The large baroque scene is completely occupied by different figures, intertwined and overlapped with each other, albeit on different levels of depth.
Sitting at the center of the scene is the Madonna, around whom the other characters revolve: in her arms is Baby Jesus, unbalanced sideways towards the infant Saint John, who holds his cross surmounted by the band with the writing \"Ecce Agnus Dei\"; in the second line there is an angel on the left, who looks in adoration at the two children, on the right a saint, recognizable in San Domenico for his iconographic attributes: the Dominican robe, but above all the star (or pole star) placed on his forehead to indicate his ability to point to Christ, and the lily he holds in his hand, a symbol of purity.
They accentuate the dynamism of the bodies, the colors of the figures, among which those of Mary's dress stand out: the red of the dress, taken from the book half hidden behind Jesus which she holds with one hand, the blue with the yellow folds of the mantle, which are also found in the angel's dress.
The color range of the flesh tones also varied considerably, with a particular contrast between the paleness of the body of the Child Jesus and the tanned complexion of the little John.
The work has undergone restoration and re-lining interventions in the past.
It is presented in a stylish frame.